Antiproliferative and antibacterial properties of biocompatible copper(II) complexes bearing chelating N,N-heterocycle ligands and potential mechanisms of action

Rodica Olar^{a b}✉, Mihaela Badea^b, Mihaela Bacalum^c, Mina Răileanu^{c d}, Lavinia Liliana Ruta^e, Ileana Cornelia FARCASANU^e, Arpad Mihai Rostas^f, Ioana Dorina Vlaicu^f, Marcela Popa^g, Mariana Carmen Chifiriuc^{g h}

1. ^aDepartment of Inorganic Chemistry, Faculty of Chemistry, University of Bucharest, 90-92 Panduri Str., 050663, Bucharest, Romania. rodica.olar@chimie.unibuc.ro
2. ^bDepartment of Inorganic Chemistry, Faculty of Chemistry, University of Bucharest, 90-92 Panduri Str., 050663, Bucharest, Romania
3. ^cDepartment of Life and Environmental Physics, Horia Hulubei National Institute for Physics and Nuclear Engineering, 30 Reactorului Str., 077125, Măgurele-Ilfov, Romania
4. ^dDepartment of Electricity, Solid State and Biophysics, Faculty of Physics, University of Bucharest, 405A Atomiştilor Str., 077125, Măgurele-Ilfov, Romania
5. ^eDepartment of Organic Chemistry, Biochemistry and Catalysis, Faculty of Chemistry, University of Bucharest, 90-92 Panduri Str., 050663, Bucharest, Romania
6. ^fLaboratory of Atomic Structures and Defects in Advanced Materials, National Institute of Materials Physics, 405A Atomiştilor Str., 077125, Măgurele-Ilfov, Romania
7. ^gDepartment of Microbiology, Faculty of Biology, University of Bucharest, 1-3 Aleea Portocalelor Str., 060101, Bucharest, Romania
8. ^h