Discovery of novel, potent, brain-permeable and orally efficacious positive allosteric modulator of alpha 7 nicotinic acetylcholine receptor [4-(5-(4-chlorophenyl)-4-methyl-2-propionylthiophen-3-yl)benzenesulfonamide], structure activity relationship and preclinical characterization.
N. Sinha, Navnath P. Karche, Mahip K. Verma, S. S. Walunj +36 more
2019Journal of Medicinal Chemistry22 citations Open access
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